Respond to each reply with APA 7th ed format include one in-text citations from different sources 5 years old or more for each reply

Respond to each reply with APA 7th ed format include one in-text citations from different sources 5 years old or more for each reply

Reply from Erika

Weight loss drugs can be a valuable adjunct to lifestyle interventions for certain patients struggling with obesity. Select one of the different classes of weight loss drugs, its mechanism of action, and the key factors healthcare professionals must consider when selecting this treatment regimen for a specific patient. How do potential side effects, contraindications, and patient preferences factor into this decision-making process?

For the past two decades, the rate of overweight and obesity continued to grow in both adult and children. Currently, there are 16% globally of adult living with overweight and obesity, while children is at 8% (World Health Organization, n.d.). Obesity is linked to many health illnesses such as diabetes, cardiovascular disease, or stroke. Despite encouraging our patient to make healthier choices by exercising or eating healthy food, weight loss drugs can definitely be a valuable adjunct to support patients who are struggling with weight loss and obesity.

Recently, GLP-1 Receptor Agonists such as Semaglutide have been extremely popular in the aspect of weight loss. This class of drugs was initially used to control glucose level for diabetic patients but incidentally found that it also aids in weight loss. According to Rosenthal (2020, pg. 414), GLP-1 receptor agonists, also called as incretin mimetics, works by augmenting the effects of incretin hormone that results in slow gastric emptying, stimulating glucose-dependent release of insulin, inhibiting postprandial release of glucagon, and suppresses appetite. This medication can cause GI symptoms such as severe heartburn, bloating, nausea, or vomiting. Additionally, this is contraindicated to patients who has history of thyroid tumor or multiple endocrine neoplasia type 2 as this medication may cause it. When deciding the best treatment course for the patient, we have to consider different factors and ultimately create a patient-focused weight loss plan.

REPLY FROM JIN

One condition that increases the risk for vitamin deficiency is chronic alcohol use disorder. Patients that frequently drink alcohol are often deficient in folate, vitamin B6, thiamine, and vitamin A. Ethanol has an inhibitory effect on the absorption of various nutrients (Butts et al., 2023). Healthcare professionals can identify these at-risk patients by obtaining a medical history. In addition, chronic alcohol use disorder can lead to damage to the liver. Alcohol related damage to the liver starts off as alcoholic fatty liver, then alcoholic hepatitis, and eventually alcoholic cirrhosis. The signs and symptoms of these conditions can present as jaundice, ascites, nausea/vomiting, and proximal muscle loss (Patel, 2023). Malnutrition is associated with the severity of the liver disease. The most important treatment for malnutrition associated with chronic alcohol use disorder and alcohol related liver damage is of course cessation of drinking. To address the nutrition deficiencies, a high protein and high energy diet should be considered. In addition, it is crucial to replace the B vitamins such as folic acid and thiamine which is often done through a “banana bag”, an IV solution containing folic acid, thiamine, multivitamins, and magnesium sulfate.

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