Research Question:
Does infliximab effectively achieve remission in Behçet’s uveitis patients?
Objectives of the Literature Review:
• Evaluate the efficacy of infliximab in achieving remission in Behçet’s uveitis patients.
• Assess the safety profile of infliximab.
The Review Will Include:
1. Introduction: Overview of Behçet’s disease, its prevalence in Saudi Arabia, and its uveitis complications.
2. Infliximab Overview: Mechanism of action, its use in autoimmune diseases, and its specific relevance to Behçet’s uveitis.
3. Efficacy Evidence: Summary of studies assessing clinical outcomes, including remission rates.
4. Safety Profile: Highlight adverse events, tolerability, and patient withdrawal rates due to side effects.
5. Comparison with Alternatives: Comparison between infliximab biologic (Remicade) and biosimilar (Remsima) as well as other biologics (e.g., adalimumab) for treating uveitis.
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